Scientific Literature

The scientific literature on saffron in relation to tissue protection is large and fast-growing.
Here are seven articles from the peer-reviewed literature; each describes its findings, and their context, for the reader to judge.
Each is labelled by the name of the first author and the year of publication.
There are hundreds more scientific articles on saffron, dealing with its effects on tissues, its toxicity, the active components; these are just a few, selected for their importance.
Much remains to be learnt about saffron and its interaction with tissues of the body; much work is underway


Alavizadeh 2014.pdf Alavizadeh 2014.pdf This paper reviews knowledge of the beneficial effects of one of the major bioactive components of saffron, crocin

Bisti 2014.pdf Bisti 2014.pdf Reviews what is known of the neuroprotective effects of saffron

Falsini 2010.pdf Falsini 2010.pdf Presents the results of a clinical trial of saffron with patients with early-stage, dry AMD

Hausenblas 2013.pdf Hausenblas 2013.pdf Reviews evidence of the effectiveness of saffron as an anti-depressant

Marongoni 2013.pdf Marongoni 2013.pdf Presents evidence that the effectiveness of saffron for AMD is independent of predisposing gentes

noorbala 2005.pdf noorbala 2005.pdf Compares the effectiveness of saffron as an antidepressant, with the effectiveness of an established antidepressant drug

piccardi_2012.pdf piccardi_2012.pdf  Follows up the study by Falsini and colleagues. It reports evidence that saffron stablises the macula for up to 14 months